MATERIAL SAFETY DATA SHEETS
MSDS No: 7784-42-1
|SUPPLIER ADDRESS:||6141 Easton Road, Bldg. 1|
PO Box 310
Plumsteadville, PA 18949-0310
|EMERGENCY PHONE NUMBER:||(215) 766-8861|
|PRODUCT NAME:||ARSINE||SYNONYMS:||Arsenic trihydride, Hydrogen arsenide|
|2. COMPOSITION, INFORMATION ON INGREDIENTS|
|Ingredient Name||Formula||CAS #||Concentration|| ACGIH TLV || OSHA PEL || MAC || Other STEL |
|ARSINE||ASH3||7784-42-1|| 99+%||0.005|| 0.05|| 0.05|| NE|
|Note: ||NE = NONE ESTABLISHED||S/A = SIMPLE ASPHYXIANT|
|3. HAZARD INDENTIFICATION|
* * * EMERGENCY OVERVIEW * * *
Poisonous, flammable liquid and gas under pressure.
Cancer suspect agent.
Causes severe, blood, liver, kidney and other organ damage.
Symptoms may be delayed.
May form explosive mixtures with air.
POTENTIAL HEALTH EFFECTS
ROUTES OF ENTRY: Inhalation, Skin
ACUTE EFFECTS: Arsine is an extremely toxic gas.Symptoms of exposure may be delayed up to 2 days.Arsine causes destruction of the red blood cells and severe injury to liver, kidney and central nervous system.Symptoms of exposure include nausea, vomiting, headache, tightness in the chest, pain in the abdomen and loins and tingling sensations in the extremities and face.Dark red urine may be noticed 4 to 6 hours after exposure and jaundice may be seen 24 to 48 hours after exposure.Bone marrow depression and peripheral neuropathies may also occur.Liquid may cause frostbite.Concentrations of 250 ppm for 30 minutes are fatal, and at 30 to 100 ppm can cause symptoms in just a few hours.ANY TYPE OF EXPOSURE TO ARSINE SHOULD BE TREATED AS A POTENTIALLY DANGEROUS DOSE AND FIRST AID PROCEDURE SHOULD BE EXERCISED EVEN IF SYMPTOMS ARE NOT EVIDENT.
CHRONIC EFFECTS: At low concentrations (less than 0.5 ppm) can cause jaundice, hemolytic anemia, and bronze discoloration of the skin.
MEDICAL CONDITIONS AGGRAVATED BY OVEREXPOSURE: None known
OTHER EFFECTS OF OVEREXPORSURE: None
CARCINOGENICITY (US ONLY):
NTP - No
IARC MONOGRAPHS - No
OSHA REGULATED - No
INHALATION: Immediately remove victim to fresh air.If breathing has stopped, give artificial respiration.If breathing is difficult, give oxygen.
EYE CONTACT: Immediately flush eyes, including under the eyelids, gently but thoroughly with plenty of running water for at least 15 minutes.
SKIN CONTACT: Immediately flush with copious amounts of water for at least 15 minutes while removing contaminated clothing.
IN EVENT OF EXPOSURE, CONSULT A PHYSICIAN
NOTE TO PHYSICIAN: Support cardiovascular and respiratory function. Ensure adequate hydration with alkaline solutions and diuretics. Test for arsenic via plasma hemoglobin, WBC count, urinary hemoglobin counts. Dietary intake of fish, shellfish, red wine, tobacco, and contaminated drinking water may contribute to urinary arsenic findings. Patients should avoid these items 48 to 72 hours prior to urine collection for chronic exposure determination. Check BUN, creatine clearance. Dimercaprol (BAL) is of no use because it does not protect against hemolysis. Perferred treatment is exchange transfusion to remove damaged RBC's and decrease the arsenic burden and if renal failure develops, hemodialysis. As a rough guide, perform replacement transfusion if serum hemoglobin reaches levels of 1.5 g/dL or if oliguria develops.
|5. FIRE FIGHTING MEASURES|
FLASH POINT: N/Av
AUTOIGNITION TEMPERATURE: N/Av
FLAMMABLE LIMITS: Vol.%
EXTINGUISHING MEDIA: For small fires, let burn unless leak can be stopped.For large fires, use water spray, fog, or regular foam.
SPECIAL FIRE FIGHTING INSTRUCTION AND EQUIPMENT: Wear self-contained breathing apparatus and full protective clothing.Keep fire exposed cylinders cool with water spray.If possible, stop the product flow.
HAZARDOUS COMBUSTION PRODUCTS: Arsenic Oxide
UNUSUAL FIRE AND EXPLOSION HAZARDS: If cylinders are exposed to high temperatures, arsine will decompose rapidly to form arsenic and hydrogen.Pressure can build up rapidly to cause cylinder faliure.Vapors may travel a considerable distance to the source of ignition and flash back.
|6. ACCIDENTAL RELEASE MEASURES|
CLEAN UP PROCEDURES: Evacuate and ventilate area.Remove leaking cylinder to exhaust hood or safe outdoor area.Shut off source if possible and remove source of heat.
SPECIALIZED EQUIPMENT: None
PRECAUTIONS TO BE TAKEN IN HANDLING: Secure cylinder when using to protect from falling.Use suitable hand truck to move cylinders.
PRECAUTIONS TO BE TAKEN IN STORAGE: Store in well ventilated areas.Store away from heat, flame, and sparks.Keep valve protection cap on cylinders when not in use.
|8. EXPOSURE CONTROLS / PERSONAL PROTECTION|
ENGINEERING CONTROLS: Provide adequate general and local exhaust ventilation to maintain concentrations below exposure and flammable limits.
EYE / FACE PROTECTION: Safety glasses
SKIN PROTECTION: Impervious gloves, coveralls, boots, and/or other resistant protective clothing.
RESPIRATORY PROTECTION: In case of leakage, use self-contained breathing apparatus.
OTHER PROTECTIVE EQUIPMENT: Safety shoes when handling cylinders.
|9. PHYSICAL AND CHEMICAL PROPERTIES|
ODOR: Garlic like odor.
PHYSICAL PRESSURE: Gas
VAPOR PRESSURE: @20 deg.C: 11000 mm Hg
VAPOR DENSITY (AIR=1): 2.69
BOILING POINT (C): -62
SOLUBILITY IN WATER: 20 cm3/100 cm3
SPECIFIC GRAVITY (H2O=1): Gas
EVAPORATION RATE: Gas
ODOR THRESHOLD: 0.05 ppm
|10. STABILITY AND REACTIVITY|
CONDITIONS TO AVOID: Storage in poorly ventilated areas.Storage near a heat source. Avoid temperatures exceeding 300 deg. C.
MATERIALS TO AVOID: Oxidants such as oxygen and chlorine.Contact with brass and aluminum fittings should be avoided.Reacts violently with fluorine, chlorine, ammonia and nitric acid.
HAZARDOUS POLYMERIZATION: Will not occur.
HAZARDOUS DECOMPOSITION: Arsenic and hydrogen.
|11. TOXICOLOGICAL INFORMATION|
LETHAL CONCENTRATION (LC50): 20 ppm, rat 1 hour.
LETHAL DOSE 50 (LD50): N/Ap
REPRODUCTIVE EFFECTS: N/Ap
|12. ECOLOGICAL INFORMATION|
No adverse ecological effects are expected.
|13. DISPOSAL CONSIDERATIONS|
WASTE DISPOSAL METHOD: Dispose of non-refillable cylinders in accordance with federal, state and local regulations. Allow gas to vent slowly to atmosphere in an unconfined area or exhaust hood. If the cylinders are the refillable type, return cylinders to supplier with any valve outlet plugs or caps secured and valve protection caps in place.All system exhaust should be piped into a neutralizing solution such as aqueous solution of permanganate or iodine.
|14. TRANSPORT INFORMATION|
DOT DESCRIPTION (US ONLY):
PROPER SHIPPING NAME: Arsine
HAZARD CLASS: 2.3 (poison), Hazard Zone A
INDENTIFICATION NUMBER: UN2188
REPORTABLE QUANTITIES: 1 lb.
LABELING: POISON GAS, FLAMMABLE GAS
ADR / RID (EU Only): Class 2, 1tf
SPECIAL PRECAUTIONS: Cylinders should be transported in a secure upright position in a well ventilated truck.
|15. REGULATORY INFORMATION|
OSHA: Process Safety Management: Materials are not listed in appendix A of 29 CFR 1910.119 as highly hazardous chemicals.
TSCA: Material is listed in TSCA inventory.
SARA: The threshold planning quantity for this material is100 lbs.
EU NUMBER: 232-066-3
NUMBER IN ANNEX 1 OF DIR 67/548: Material is listed in annex 1.
EU CLASSIFICATION: N/Av
OTHER PRECAUTIONS: Protect containers from physical damage. Do not deface cylinders or labels. Cylinders should be refilled by qualified producers of compressed gas. Shipment of a compressed gas cylinder which has not been filled by the owner or with his written consent is a violation of federal law (49 CFR).
ABBREVIATIONS: N/Ap - Not Applicable N/Av - Not Available SA - Simple Asphyxiant NE - None Established
DISCLAIMER: Information included in this document is given to the best of our knowledge, however, no warranty is made that the information is accurate or complete. We do not accept any responsibility for damages by the use of the document.